Some say they have experienced “COVID arm” from the Moderna vaccine in particular. If the swelling persists or other health issues coincide with it, a trip to the doctor may be needed. Lymph nodes are an essential part of the immune system, housing white blood cells to fight infection. While swollen lymph nodes may be worrisome at first, this has been deemed as a perfectly normal reaction that will fade, with 11.6 per cent of patients in Moderna’s trials and 0.3 per cent of Pfizer-BioNTech’s patients reporting swelling after their first dose. Recent research has found those reporting this side effect experienced it in the axilla (basically the arm pit) of the injected arm several days after vaccination. Swollen lymph nodes have been reported by Moderna, Pfizer-BioNTech and AstraZeneca-Oxford. Here are five frequently described ones and what we know about them so far: 1) Lymphadenopathy However, as millions of people are vaccinated, other potential side effects have become the subject of online discourses, leaving many wondering if the medical mysteries they’re experiencing are linked to their vaccinations. Pfizer-BioNTech, Moderna, AstraZeneca-Oxford and Janssen have all reported similar side effects with their COVID-19 vaccines: redness, pain or swelling at the site of injection, fatigue, headache, muscle pain and fever. It is only when the vaccine is widely distributed that rarer or abstract side effects might come to light. These side effects are common in almost any vaccination, but especially so for COVID-19 vaccines.Įven after the third phase of clinical trials and the beginning of a vaccine’s distribution to the public, vaccines continue to be monitored and reviewed to confirm their safety and that their benefits outweigh the risks. Local reactions are specific to one part of the body, such as pain where the vaccine is injected systemic reactions are felt throughout the body, like a fever or fatigue. Side effects also are categorized as local or systemic reactions. According to the Centers for Disease Control’s website, the vaccine is given to individuals who match characteristics “similar to those for whom the new vaccine is intended.” Phase 3 involves dosing tens of thousands of participants to test the vaccine for efficacy and safety. Food and Drug Administration’s (FDA) second phase is described as an expansion of the first and is similar to Canada’s. Phase 2 trials are typically where we start (…) looking at how the immune system responds to the vaccines.” “Once we’ve determined that the vaccine among that very, very small subset is safe, we then go into a Phase 2 study. Phase 1 involves a small number of participants to “assess safety, toxicity and dosage,” says Catharine Chambers, an epidemiologist and public health researcher. This is typically divided into three phases. Side effects are analyzed throughout an extensive clinical trial process when a vaccine is in development. And though COVID-19 vaccines are reported to have more intense side effects than a regular flu shot, this is merely a sign that your immune system is doing its job. While there is an abundance of anecdotal reports of odd side effects from the vaccines, few are proven to be caused by them. Some of the expected side effects of COVID-19 vaccines include a sore arm, fatigue and a mild fever – but what about strange dreams?
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